Synthra MeIplus

Synthra MeIplus is a flexible and completely automated synthesis system for routine production of a wide variety of [11C]carbon-labeled compounds based on the generation of gas-phase [11C]methyl iodide or optional [11C]methyl triflate synthesis. The [11C]methyl iodide can be used for solid support heterogeneous reactions for the synthesis of e. g. [11C]choline, [11C]methionine.

Synthra provides its own software with manual and automatic modes of operation.

Synthra Graphical User Interface

Included Features:

  • C-11 gas phase chemistry (Yield >50% for [11C]CH3I in 7min)
  • Simple creation of user-defined synthesis variations
  • Eight heating zones, five with cooling capabilities (-196 °C – 950 °C)
  • Closed reaction vessel (-196 °C - 200 °C)
  • Three electronic flow controller for highly defined gas flow rates
  • Six shielded radiation detectors for in-process feedback
  • Built-in self-cleaning System
  • Built-in semi preparative Radio/UV-HPLC system (max. flow: 40 mL/min) with fixed wavelength detector (255 or 280 nm) and optional quaternary gradient mixing chamber
  • High resolution dispenser 0-50.000 steps, 2.5 ml or 5 ml syringe
  • Automatic pneumatic injection valve with a 0.5 to 2.5 mL sample loop
  • See detailed specification for more...
PDF Detailed specification of MeIplus radiosynthesizer


Number of consecutive [11C]CH3I synthesis 10, then exchange of NaOH trap
Dimensions 53 x 46 x 48 cm (w x d x h)
Weight Approx. 43 Kg
Hot Cell (minimum size) 65 x 55 x 55 cm (w x d x h)