Synthra MeIplus Reaction Loop

Synthra MeIplus Reaction Loop is a flexible and completely automated synthesis system for routine production of wide variety of [11C]carbon-labeled compounds based on the generation of gas-phase [11C]methyl iodide or optional [11C]methyl triflate synthesis.

The system contains a closed reaction loop (800 μL) with integrated cooling (-180 - 200°C) to reduce synthesis time.

Synthra provides its own software with manual and automatic modes of operation.

Synthra Graphical User Interface

Included Features:

  • Simple creation of user-defined synthesis variations
  • Seven heating zones, three with cooling capabilities (-196 °C – 950 °C)
  • Closed reaction loop with integrated cooling (-196 °C – 200 °C)
  • Three electronic flow controller for highly defined gas flow rates
  • Six shielded radiation detectors for in-process feedback
  • Built-in self-cleaning System
  • Built-in semi preparative Radio/UV-HPLC system (max. flow: 40 mL/min) with fixed wavelength detector (255 - 280 nm) and optional quaternary gradient mixing chamber
  • High resolution dispenser 0-50.000 steps, 2.5 ml or 5 ml syringe
  • Automatic pneumatic injection valve with a 0.5 to 1.5 mL sample loop
  • See detailed specification for more...
PDF Detailed specification of MeIplus Reaction Loop radiosynthesizer


Disclaimer: Yields and specific activity of labeled [11C]tracers are dependent on use of proper technique and appropriate reagents.

Yields > 50% for [11C]CH3I in less than 7 min
Dimensions 53 x 45 x 48 cm (w x d x h)
Weight Approx. 42 Kg
Hot Cell (minimum size) 65 x 55 x 55 cm (w x d x h)